Lorenzo Sempere is an Assistant Professor in the Department of Radiology and a faculty member of the Precision Health Program at MSU. His research focuses on micro-RNA-based diagnostic and therapeutic applications for breast and pancreatic cancer.
Dr. Sempere received his Ph.D. in Genetics from Geisel School of Medicine at Dartmouth, where he also completed his postdoctoral training. Before joining MSU, Dr. Sempere held faculty positions at Geisel School of Medicine and Van Andel Research Institute.
The Sempere Laboratory pursues complementary lines of translational research in cancer prevention and early detection as well as microRNA-based diagnostic and therapeutic applications with a disease focus on breast and pancreatic cancer. The lab uses contextual high-content tissue analyses, 3D modeling, allograft transplantations, genetically engineered animal models and other tools to characterize molecular and cellular tumor heterogeneity and to functionally dissect cancer cell-stroma interactions as well as to identify microRNA-regulated gene networks in development (organ formation), physiology and disease (cancer initiation and progression).