Ron Chandler is an Associate Professor in the Department of Obstetrics, Gynecology, and Reproductive Biology. His research focuses on the molecular mechanisms involved in chromatin remodeling, and how disruption of these mechanisms contributes to endometriosis and gynecological cancers.
Dr. Chandler received his Ph.D. in Molecular Physiology and Biophysics from Vanderbilt University. He completed his postdoctoral training at the University of North Carolina at Chapel Hill with fellowship funding from the American Cancer Society.
Dr. Chandler’s research focuses on genes and signaling pathways important for cellular homeostasis in the female reproductive system, and which mutations cause this system to go awry, leading to tumor formation. Current research focuses on ARID1A, a known tumor suppressor gene that is also mutated in endometriosis. The lab also interrogates SWI/SNF PI3-kinase pathway crosstalk, and the epigenetic mechanisms allowing cells to adapt to stress and inflammation.