Bin Chen is an Assistant Professor in the Department of Pediatrics and Human Development. His research focuses on developing computational methods and tools, in collaboration with bench scientists and clinicians, to discover new or better therapeutic candidates.
Dr. Chen received his Ph.D. in Informatics from Indiana University and completed his postdoctoral training in bioinformatics at Stanford University. Prior to joining MSU, he was an Assistant Professor in the Institute for Computational Health Sciences at the University of California, San Francisco. He is also the founder of DahShu, a non-profit organization promoting research and education in data sciences.
The Chen Lab is interested in leveraging “big data” and artificial intelligence to connect the various components (patients, tissues, in vitro models and in vivo models) needed for translational research. Using a systems-based approach, Dr. Chen’s lab has successfully identified drug candidates for Ewing’s sarcoma, liver cancer, and basal cell carcinoma. In a pan-cancer analysis, the lab found that the potency to reverse cancer gene expression correlates to drug efficacy. Additionally, Dr. Chen’s team is developing methods to integrate single-cell data and deep learning approaches for personalized cancer therapy.