Jeremy Prokop is an Assistant Professor in the Department of Pediatrics and Human Development. His research focuses on understanding genes and genetic variants, using computational tools to generate testable hypotheses regarding disease mechanisms and pharmacological intervention.
Dr. Prokop received his Ph.D. in Integrated Bioscience from the University of Akron, and completed his postdoctoral training at the Medical College of Wisconsin. Prior to joining MSU, he was a Senior Scientist at HudsonAlpha Institute for Biotechnology.
The Prokop lab’s computational tools focus on deep evolutionary analysis of codon usage combined with protein modeling and molecular dynamics simulation to study genetic variants. Variants/proteins are then studied in the lab using a combination of protein biophysics, cell culture (including primary cells and induced pluripotent stem cells), gene regulation, and genomic technologies. These tools have been successfully applied to genomic insights for multiple diseases, including chronic kidney disease, mesothelioma, obesity, neurological diseases, cancer metastasis, and genetics of sex differences.